Two numbers account for most searches that reach a Greek gematria calculator. Both come from real texts, both have a documented scholarly literature, and neither is well served by the pages currently ranking for this term — none of which cite a primary source.
666 and the variant 616
The number appears in Revelation 13:18, which invites the reader to calculate it. In the Greek manuscript tradition it is written as the numeral χξϛ — chi 600, xi 60, stigma 6 — which is itself a demonstration of how Greek letters function as numbers, and a good reason the archaic letters matter.
Not all manuscripts agree. Papyrus 115, a third-century fragment from Oxyrhynchus, and Codex Ephraemi Rescriptus both read 616 (χιϛ) instead. Irenaeus, writing in the second century in Against Heresies V.30, already knew of the 616 reading and argued against it, which places the variant very early.
The most widely held scholarly explanation connects the number to the emperor Nero. Transliterating 'Neron Caesar' into Hebrew letters gives a total of 666; the Latin spelling 'Nero Caesar' drops a final nun worth 50, giving 616. That a single spelling difference accounts for both readings is the main reason the identification is taken seriously. It remains an interpretation, not a settled fact, and other candidates have been proposed.
888 and the name Jesus
Ἰησοῦς totals 888, as the worked example above shows. The observation is ancient rather than modern: it appears in the Sibylline Oracles, and Irenaeus discusses it in the same section of Against Heresies that treats 666. Early Christian writers read the number as significant partly by contrast with 666 and partly because 8 was associated with resurrection and the day after the Sabbath.
Other documented values
Ἀβρασάξ totals 365, matching the days of the year, which is why the name appears on Gnostic amulets and in magical papyri. Μίθρας was adjusted in antiquity to total 360 for similar reasons. The dove, περιστερά, totals 801, and so does alpha plus omega (1 + 800) — a pairing noted by early commentators as linking the bird of the baptism to the beginning and the end. These are documented instances of deliberate isopsephy, which is what separates them from coincidental matches.